Journal: Scientific Reports
Article Title: Simulation of transvascular transport of nanoparticles in tumor microenvironments for drug delivery applications
doi: 10.1038/s41598-024-52292-0
Figure Lengend Snippet: Comparative Analysis of Selected Studies for Literature Review.
Article Snippet: 16. , Seyedali Seyedmirzaei Sarraf , 2021 , Modeling and simulation of magnetic nanoparticles' trajectories through a tumorous and healthy microvasculature , This study employs computational 2D modeling and simulation in the COMSOL environment to analyze MNP trajectories. By considering differences between healthy and tumorous vascular networks, the study evaluates multiple geometry-close models under various magnetic field distributions. Capture efficiency, fallout coefficient, and MDT efficiency ratio are defined to assess the steering ability and potential side effects of magnetic drug targeting (MDT) , Assumptions regarding magnetic field distributions (MFD) and the selection of the optimal MFD based on particle tracing simulations introduce potential limitations in capturing the complexity of real-world magnetic environments.
Techniques: Shear, Magnetic Resonance Imaging, Imaging, Software, Clinical Proteomics, Selection, Introduce